JERUSALEM (JTA)  — Israel will not exist in 25 years, Iran’s Supreme Leader Ayatollah Ali Khamenei said.

Khamenei made the threat in a speech to the Iranian people and followed it up with a tweet on his official Twitter account later on Wednesday.

“After negotiations, in the Zionist regime they said they had no more concern about Iran for next 25 years; I’d say: Firstly, you will not see the next 25 years; God willing, there will be nothing as Zionist regime in 25 years. Secondly, until then, struggling, heroic and Jihadi morale will leave no moment of serenity for Zionists,” Khamenei said.

Khamenei also took aim at the United States, which he called the “Great Satan.”

“Iranian nation did expel this Great Satan; we barred their direct access and now we must not allow their indirect access and infiltration,” Khamenei tweeted.

“We would negotiate and reach agreement in different levels of ‘state, religion or ethnic groups’ with all countries but the Great Satan,” he also tweeted, indicating that he will not allow talks with the United States on other issues.

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